DRAW VENN DIAGRAM ONLINE SOFTWARE
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DRAW VENN DIAGRAM ONLINE SOFTWARE

However, the above-mentioned software packages also have their disadvantages. It is impossible to develop a state-of-the-art Venn tool without absorbing the strengths of the above-mentioned tools. RVenn has been developed as a systematic and easy-to-use method for calculating intersecting and overlapping members in Venn diagrams. In addition, venn supports the drawing of Venn diagrams with up to seven sets. As one of the most popular software, VennDiagram supports multiple input formats, and it can also generate Euler diagrams in addition to Venn. In the R environment, one of the most popular platforms in biomedical data visualizations, many packages are available to plot a Venn diagram including VennDiagram ( Chen and Boutros, 2011), colorfulVennPlot ( Noma and Manvae, 2013), venn ( Dusa, 2020), nVennR ( Quesada, 2021), eulerr ( Larsson, 2020), venneuler ( Wilkinson, 2011), RVenn ( Akyol, 2019), and gplots ( Warnes et al., 2020), to name a few (see Table 1 for a feature comparison of these packages). When the number of sets is less than five, Venn diagrams are probably the most intuitive form of data visualization, superior to heat maps and tables. In biomedical studies, a Venn diagram is frequently used in distinguishing the membership of various types of data, such as compounds, genes, pathways, and species. The package is an open-source software released under the GPL-3 license, and it is freely available through CRAN ( ).ДЄ Venn diagram is a widely used diagram that shows the relationships between multiple sets.

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To date, ggVennDiagram has been cited in more than 10 publications, and its source code repository has been starred by more than 140 GitHub users, suggesting a great potential in applications. Therefore, high customization of every Venn plot sub-element can be fulfilled without increasing the cost of learning when the user is familiar with ggplot2 methods.

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Furthermore, we designed comprehensive objects to store the entire data of the Venn diagram, which allowed free access to both intersection values and Venn plot sub-elements, such as set label/edge and region label/filling. Satisfactory results can be obtained with minimal configurations. The ggVennDiagram is built based on ggplot2, and it integrates the advantages of existing packages, such as venn, RVenn, VennDiagram, and sf. In this study, we developed ggVennDiagram, an R package that could automatically generate high-quality Venn diagrams with two to seven sets. Venn diagrams are widely used diagrams to show the set relationships in biomedical studies.

2Department of Bioinformatics, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.

1State Key Laboratory of Agricultural Microbiology, State Environmental Protection Key Laboratory of Soil Health and Green Remediation, College of Resources and Environment, Huazhong Agricultural University, Wuhan, China.

Chun-Hui Gao 1, Guangchuang Yu 2 and Peng Cai 1*

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